Gastric Operations and Vagotomy

Gastric emptying following vagotomy and antrectomy and proximal gastric vagotomy.

Gastric emptying of solid meals labelled with 129Cs was studied in patients for up to one year after vagotomy and antrectomy or after proximal gastric vagotomy. Significant delay was found one month after vagotomy and antrectomy but this had returned to normal by six months. No delay was found after proximal gastric vagotomy. The effect of posture on gastric emptying was also studied in the sam...

Vagotomy and Gastric Tumorigenesis

Vagotomy reduces gastric acid secretion and was therefore introduced as a surgical treatment for peptic ulcers in the 1970s. Later, it was replaced by acid reducing medication, such as histamine type 2 (H2) receptor antagonists and proton pump inhibitors (PPIs). A large body of evidence has indicated that drug-induced hypochlorhydria per se does not increase the risk of gastric cancer. Early st...

Gastric fistula after proximal gastric vagotomy.

Distribution of a liquid meal within the stomach and gastric emptying after vagotomy and drainage operations.

The intragastric distribution of a radionuclide labelled liquid meal was studied in 62 patients with duodenal ulceration by means of a gamma camera imaging system. A total of 85 gastric emptying studies (23 preoperative and 62 postvagotomy tests) revealed three distinct patterns of distribution. The activity distribution in the stomach after vagotomy showed a slower rate of return and a decreas...

Effect of Proximal Gastric Vagotomy

Methods We calculated gastric HCO3 and H+ secretion, as well as nonparietal and parietal volume secretion, in 15 duodenal ulcer patients who had previously undergone successful proximal gastric vagotomy, 15 unoperated duodenal ulcer patients, and 15 normal control subjects. Basal HCO3secretion was not significantly altered after vagotomy, while basal H+ secretion, parietal volume and nonparieta...